The number of potential recipients awaiting their life-saving organ in the United States grows daily. The number waiting is over 100,000 and there are not enough organ donors to help all of them to receive the organ transplants they need. Traditionally, HIV-positive potential donors were excluded from donation. Then, on November 21, 2013, the HOPE Act (HIV Organ Policy Equity Act) was signed into law. This law makes it possible for us to transplant organs from HIV-positive donors into HIV positive recipients who may be willing to accept an organ from an HIV-positive donor. We can also use research to better understand how HIV-positive organs can help those in need to receive life-saving transplants. By offering HIV-positive donor organs to HIV-positive recipients waiting for a transplant, we can reduce the number of people waiting for transplants, saving the lives of both HIV-positive and HIV-negative people.